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SHA-68
SHA-68

Item number: Cay21512-1

SHA-68 is an antagonist of the neuropeptide S receptor (NPSR, IC50s = 22 and 23.8 nM for the NPSR Asn107 and NPSR Ile107 isoforms, respectively). It is selective for NPSR over a panel of 14 G protein-coupled receptors exhibiting no activity at a concentration of 10 µM. SHA-68 (50 mg/kg) reduces NPS-induced...
Keywords: N-[(4-fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide
Application: NPSR antagonist
CAS 847553-89-3
MW: 445.5 D
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