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Item number: AG-CR1-3673-M005

Synthetic. Chemical. CAS: 847499-27-8. Formula: C21H28BN3O5. MW: 413.3. Synthetic. Potent, selective, reversible orally bioavailable proteasome inhibitor. Synthetic P2 threonine boronic acid. Targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50=3.8nM). Cross-reacts and inhibits the...

Keywords:	NPH 007098, CT 47098, CIP 18770,...
Application:	Proteasome inhibitor
CAS	847499-27-8
MW:	413,3 D

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Delanzomib

Item number: Cay23557-1

Delanzomib is an orally bioavailable inhibitor of chymotrypsin-like proteasome activity (IC50 = 3.8 nM in isolated human erythrocytes) that only marginally inhibits tryptic and peptidyl glutamyl proteasome activity. Delanzomib pre-treatment (20 nM) in vitro inhibits IkappaBalpha degradation, NF-kappaB activation,...

Keywords:	CEP-18770,...
Application:	Antineoplastic, Proteasome inhibitor
CAS	847499-27-8
MW:	413.3 D

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