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Item number: TGM-T17209-100mg

Description: UVI 3003 is a highly selective antagonist of the retinoid X receptor, inhibiting Xenopus and human RXRalpha in Cos7 cells with IC50 values of 0.22 µM and 0.24 µM, respectively. Target: Retinoid Receptor, Autophagy. Smiles: CCCCCOc1cc2c(cc1-c1cc(\C=C\C(O)=O)ccc1O)C(C)(C)CCC2(C)C. References: Zhu J, et...

Application:	RXR antagonist
CAS	847239-17-2
MW:	436.58 D

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UVI3003

Item number: Cay16026-5

UVI3003 is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity. At 1 µM, UVI3003 does not affect the corepressor interaction capacity of the RARalpha subunit in the RAR-RXR heterodimer configuration. This compound can be used to isolate the contribution of RXR to the function of RXR...

Keywords:	3-[4-hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid
Application:	RXR antagonist
CAS	847239-17-2
MW:	436.6 D

From 130.00€ *

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