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Item number: TGM-T21023-100mg

Description: Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. It is the first member of a new class of drugs called diarylquinolines. Target:...

Keywords:	R 403323, R-403323, TMC 207, R403323, TMC207, TMC-207
CAS	845533-86-0
MW:	671.59 D

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Bedaquiline Fumarate

Item number: LKT-B165121.5

Bedaquiline is a diarylquinoline found to be useful in treating multidrug-resistant tuberculosis. In mouse models of TB, bedaquiline has significantly shortened the treatment regimen. A long-acting injectable formulation has been shown to have prolonged bactericidal activity. Bedaquiline inhibits ATP-synthase, and...

Keywords:	(1R,2S)-1-(6-Bromo-2-methoxy-3-quinolinyl)-4-(dimethylamino)-2-(1-naphthyl)-1-phenyl-2-butanol (2E)-2-butenedioate (1:1)
Application:	Antibacterial (tuberculostatic), ATP synthase inhibitor
CAS	845533-86-0
MW:	671.59 D

From 182.00€ *

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