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Bretazenil
Item number: Cay28411-5
Bretazenil is a positive allosteric modulator of GABAA receptors with anticonvulsant and anxiolytic activity. It potentiates GABA-gated chloride currents in rat cortical neurons and in HEK293 cells expressing alpha1beta1gamma2 subunit-containing GABAA receptors (EC50s = 60 and 10 nM, respectively). Bretazenil...
| Keywords: | Ro 16-6028, (13aS)-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic... |
| Application: | GABA-A receptor positive allosteric modulator |
| CAS | 84379-13-5 |
| MW: | 418.3 D |
From 50.00€
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Bretazenil
Item number: Cay37274-1
Bretazenil (Cay-37274) is an analytical reference standard categorized as a GABAA receptor positive allosteric modulator. Bretazenil has anxiolytic-like effects in mice. It induces self-administration in rhesus monkeys but has a lower physical dependence liability in mice compared with benzodiazepines. This product...
| Keywords: | Ro 16-6028, 8-bromo-11,12,13,13aS-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid,... |
| Application: | Analytical reference standard, GABA-A receptor positive allosteric modulator |
| CAS | 84379-13-5 |
| MW: | 418.3 D |
From 158.00€
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