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Item number: Cay10006317-100

Mifepristone is an antagonist of glucocorticoid, progesterone, and androgen receptors (Kis = 0.1, 0.64, and 0.65 nM, respectively). It is selective for these receptors over the mineralocorticoid receptor (MR), estrogen receptor alpha (ERalpha), and ERbeta (Kis = 640, >200, and >750 nM, respectively). In cell-based...

Keywords:	RU-486, 11beta-[4-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one
Application:	PR antagonist, GR antagonist
CAS	84371-65-3
MW:	429.6 D

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Mifepristone

Item number: LKT-M3321.1

A progesterone receptor antagonist. It is an effective late post-coital contraceptive. Active against ovarian cancer, and induces apoptosis through modulation of HPV E6/E7 in dexamethasone treated cervical cacinoma cells.

Keywords:	RU-38486, RU-486
Application:	Glucocorticoid receptor antagonist
CAS	84371-65-3
MW:	429,59 D

From 54.00€ *

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