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WH-4-023
WH-4-023

Item number: TGM-T1811-100mg

Description: WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK. Target: Src. Smiles: COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(cc3)N3CCN(C)CC3)n2)c(OC)c1. References: Martin MW, et al. J Med Chem. 2006, 49(16), 4981-4991.
Keywords: KIN112, KIN001-112, Dual LCK/SRC inhibitor
Application: Lck / Src inhibitor
CAS 837422-57-8
MW: 568.67 D
From 47.00€ *
Review
WH-4-023
WH-4-023

Item number: Cay9002067-1

WH-4-023 is a selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively). It inhibits the related kinases p38alpha and KDR at >300-fold higher concentrations (IC50s = 1.3 and 0.65 µM, respectively). At 1 µM, it has been used in combination with PD...
Keywords: N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-carbamic acid, 2,6-dimethylphenyl ester
Application: Lck / Src inhibitor
CAS 837422-57-8
MW: 568.7 D
From 53.00€ *
Review
WH-4-023
WH-4-023

Item number: LKT-W2800.1

Lck, Src, SIK inhibitor.
Keywords: KIN112
Application: Lck, Src, SIK inhibitor
CAS 837422-57-8
MW: 568.68 D
From 178.00€ *
Review