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L-Buthionine-(S,R)-Sulfoximine
Item number: Cay14484-250
L-Buthionine-(S,R)-sulfoximine is an irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki = 25 µM). It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC50s = 4.9, 18, 8.5, and 26.5 µM, respectively). L-Buthionine-(S,R)-sulfoximine (100µM)...
| Keywords: | BSO, NSC 326231, 2S-amino-4-(S-butylsulfonimidoyl)-butanoic acid |
| Application: | Oxidative stress inducer |
| CAS | 83730-53-4 |
| MW: | 222.3 D |
From 109.00€
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L-BUTHIONINE-(S,R)-SULFOXIMINE
Item number: TGM-T5371-100mg
Description: L-Buthionine-(S,R)-sulfoximine, a cell-permeable and irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki <100 µM), induces oxidative stress in cells by depleting GSH. Target: Ferroptosis, Others. Smiles: CCCCS(=N)(=O)CC[C@H](N)C(O)=O. References: Marengo B, et al. Mechanisms of BSO...
| Keywords: | L-Butionine sulfoximine |
| Application: | Oxidative stress inducer |
| CAS | 83730-53-4 |
| MW: | 222.31 D |
From 33.00€
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