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Item number: TGM-T2088-100mg

Description: APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively. Target: GPR, Potassium Channel, P450. Smiles: CC(C)OC(=O)N1CCC(CC1)Oc1ncnc2n(ncc12)-c1ccc(cc1F)S(C)(=O)=O. References: Semple G, et al. Bioorg Med Chem Lett. 2011 May 15,21(10):3134-41.

Keywords:	APD 668
CAS	832714-46-2
MW:	477.51 D

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APD668

Item number: Cay17642-5

GPR119, a glucose-dependent insulinotropic receptor, is a G protein-coupled receptor that is expressed in pancreatic beta-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine (Cay-10172) and oleoyl ethanolamide (Cay-90265) increases intracellular cAMP levels and...

Keywords:	JNJ-28630368, 4-[[1-[2-fluoro-4-(methylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy]-1-piperidinecarboxylic acid,...
Application:	GPR119 agonist
CAS	832714-46-2
MW:	477.5 D

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