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(+)-Etomoxir (sodium salt)
Item number: Cay11969-5
(+)-Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT1), an enzyme that combines fatty acyl-CoAs with carnitine for transport into the mitochondria for beta-oxidation. It inhibits fatty acid oxidation in hepatocytes in vitro (IC50s = 0.1, 1, and 10 µM for human, guinea pig, and rat...
| Keywords: | (R)-(+)-Etomoxir, (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylic acid monosodium salt |
| Application: | Irreversible CPT1 / carnitine O-palmitoyltransferase 1 inhibitor |
| CAS | 828934-41-4 |
| MW: | 320.7 D |
From 98.00€
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Etomoxir sodium salt
Item number: TGM-T4535-100mg
Description: Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis. Etomoxir sodium salt has antitumor activity. Target: Apoptosis, Others. Smiles: [Na+].[O-]C(=O)[C@@]1(CCCCCCOc2ccc(Cl)cc2)CO1. References: Cheng S, et al. Fatty...
| Keywords: | (R)-Etomoxir sodium salt, Na salt, Etomoxir |
| Application: | Irreversible carnitine palmitoyltransferase-1 (CPT-1a) inhibitor |
| CAS | 828934-41-4 |
| MW: | 320.74 D |
From 55.00€
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(+)-Etomoxir . Na
Item number: AG-CR1-3688-M025
Irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1a) a mitochondrial enzyme involved in fatty acid beta-oxidation. CPR-1a on the outer face of the inner mitochondrial membrane, consequently prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from...
| Keywords: | (R)-(+)-Etomoxir Na, (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt |
| Application: | Irreversible carnitine palmitoyltransferase-1 (CPT-1a) inhibitor |
| CAS | 828934-41-4 |
| MW: | 320.8 D |
From 77.00€
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