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Item number: Cay40786-10

GW 870086 is a cyano- and isopropyl-substituted derivative of the synthetic corticosteroid and glucocorticoid receptor agonist fluticasone propionate (Cay-20703). It selectively inhibits TNF-alpha-induced transcriptional activity of NF-kappaB in a reporter assay using A549 cells (IC50 = 0.08 nM) over a panel of 50...

Keywords:	6alpha,9-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-[[(2,2,3,3-tetramethylcyclopropyl)carbonyl]oxy]-androsta-1,4...
Application:	Fluticasone propionate derivative
CAS	827319-43-7
MW:	559.6 D

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