2 products were found matching "825658-06-8"!
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ML335
Item number: TGM-T4224-100mg
Description: ML335 is a selective activator of TREK-1 and TREK-2. Target: Potassium Channel. Smiles: CS(=O)(=O)Nc1ccc(cc1)C(=O)NCc1ccc(Cl)cc1Cl. References: Lolicato M, et al. K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature. 2017 Jul 20,547(7663):364-368.
| Application: | K2P2.1/TREK1 / K2P10.1/TREK2 activator |
| CAS | 825658-06-8 |
| MW: | 373.25 D |
From 57.00€
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ML-335
Item number: Cay27635-10
ML-335 is an activator of the two-pore domain potassium channels K2P2.1/TREK1 and K2P10.1/TREK2 (EC50s = 14.3 and 5.2 µM, respectively, in Xenopus oocytes). It is selective for K2P2.1/TREK1 and K2P10.1/TREK2 channels over K2P4.1/TRAAK channels. ML-335 activates K2P2.1/TREK1 by binding to the C-type gate, which is...
| Keywords: | N-[(2,4-dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]-benzamide |
| Application: | K2P2.1/TREK1 / K2P10.1/TREK2 activator |
| CAS | 825658-06-8 |
| MW: | 373.3 D |
From 85.00€
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