Description: Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis and bacterial cell growth. Target: Antibacterial,...

Rifaximin is an antibiotic derived from rifamycin SV (Cay-21441) that inhibits the growth of a variety of Gram-positive and Gram-negative bacteria in vitro, including Staphylococcus, Streptococcus, Enterococcus, H. influenzae, and N. gonorrhoeae (MIC50s = =0.015, 50 = ~20 µM) that reduces colonic damage, rectal...

A rifamycin derivative. It is a non-absorbable broad-spectrum antibiotic that possesses in vitro activity against a wide range of bacteria. It acts by inhibiting bacterial ribonucleic (RNA) synthesis.