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AZD 1981
AZD 1981

Item number: Cay20763-5

AZD 1981 is a DP2/CRTH2 receptor antagonist (IC50 = 3.98 nM). It is selective for DP2 over a panel of receptors, ion channels, transporters, and enzymes, including DP1, COX-1, and COX-2, at 10 µM. AZD 1981 (3-100 nM) inhibits increases in the expression of CD11b, a cell adhesion molecule, induced by...
Keywords: 4-(acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1H-indole-1-acetic acid
Application: PGD2 receptor antagonist
CAS 802904-66-1
MW: 388.9 D
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