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KYP-2047

Item number: TGM-T8657-100mg

Description: KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor. Target: Others. Smiles: C(=O)([C@H]1N(C(CCCC2=CC=CC=C2)=O)CCC1)N3[C@H](C#N)CCC3. References: T T Myöhänen 1 , M J Hannula, R Van Elzen,et al.A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and...

Application:	Prolyl endopeptidase inhibitor
CAS	796874-99-2
MW:	339.43 D

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KYP-2047

Item number: Cay39180-1

KYP-2047 is an inhibitor of prolyl endopeptidase (Ki = 0.02 nM for the porcine enzyme). It inhibits hydrogen peroxide-induced aggregation of alpha-synuclein in SH-SY5Y cells expressing wild-type, alpha-synucleinA30P, or alpha-synucleinA53T in in vitro models of Parkinson's disease when used at a concentration of 1...

Keywords:	(2S)-1-[[(2S)-1-(1-oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile
Application:	Prolyl endopeptidase inhibitor
CAS	796874-99-2
MW:	339.4 D

From 81.00€ *

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