Description: Cefixime (FR-17027) is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting...

Cefixime is a cephalosporin antibiotic. It is active against numerous Gram-negative bacteria, including clinical isolates of E. coli, K. pneumoniae, and P. mirabilis (MIC90s = 3.13, 0.2, and =0.025 µg/ml, respectively), as well as clinical isolates of the Gram-positive bacteria S. pneumoniae and S. pyogenes (MIC90s...