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NGI-1
Item number: TGM-T7366-100mg
Description: NGI-1 (ML414) is a cell-permeable inhibitor of oligosaccharyltransferase (OST) that can effectively reduce virus infectivity without affecting cell viability. Target: Virus Protease. Smiles: CN(C)S(=O)(=O)c1ccc(N2CCCC2)c(c1)C(=O)Nc1ncc(C)s1. References: Lopez-Sambrooks C , Shrimal S , Khodier C , et al....
| Keywords: | ML414 |
| Application: | OST (oligosaccharyltransferase ) inhibitor |
| CAS | 790702-57-7 |
| MW: | 394.51 D |
From 37.00€
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NGI 1
Item number: Cay31519-5
NGI 1 is an oligosaccharyltransferase (OST) inhibitor. It binds to and stabilizes the STT3B catalytic subunit of OST in a cellular thermal shift assay (CETSA) and inhibits N-linked glycosylation in a reporter assay using D54 ER-LucT cells (IC50 = 1.1 µM). NGI 1 (10 µM) reduces glycosylation and membrane localization...
| Keywords: | N-linked Glycosylation Inhibitor 1, 5-[(dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)-benzamide |
| Application: | OST (oligosaccharyltransferase ) inhibitor |
| CAS | 790702-57-7 |
| MW: | 394.5 D |
From 61.00€
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