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Item number: Cay14539-100

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...

Keywords:	D-2-Amino-5-Phosphonovaleric Acid, D-APV, 5-phosphono-D-norvaline
Application:	NMDA receptor antagonist
CAS	79055-68-8
MW:	197.1 D

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D-AP5

Item number: TGM-T10930-10mg

Description: D-AP5 (D-APV) is an NMDA receptor antagonist. Target: iGluR, NMDAR. Smiles: C(C[C@H](C(O)=O)N)CP(=O)(O)O. References: Davis S, et al. The NMDA receptor antagonist D-2-amino-5-phosphonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that...

Keywords:	D-APV, D-2-Amino-5-phosphonovaleric acid
CAS	79055-68-8
MW:	197.13 D

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