- Search results for 790245-61-3
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2 products were found matching "790245-61-3"!
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Item number: TGM-T60030-2mg
Description: NCT02, a cyclin K degrader, promotes the ubiquitination and proteasomal degradation of cyclin K (CCNK) and its complex partner CDK12, showing promise for metastatic colorectal cancer (CRC) research[1]. Target: Others. Smiles: Cc1cnc(NC(=O)Cc2coc3cc4CCCc4cc23)s1
Application: | Cyclin K degrader |
CAS | 790245-61-3 |
MW: | 312.39 D |
58.00€
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Item number: Cay39568-1
NCT-02 is a degrader of cyclin K. It reduces the levels of cyclin K in patient-derived colorectal cancer (CRC) cells in a concentration-dependent manner. NCT-02 inhibits cancer cell proliferation in CRC tissue samples isolated from the colon (IC50s = 0.9-20.6 µM), as well as from hepatic, lung, and rectal metastases...
Keywords: | 6,7-dihydro-N-(5-methyl-2-thiazolyl)-5H-indeno[5,6-b]furan-3-acetamide |
Application: | Cyclin K degrader |
CAS | 790245-61-3 |
MW: | 312.4 D |
From 40.00€
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