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Item number: Cay20872-10

MY-5445 is a selective inhibitor of the cyclic GMP (cGMP) phosphodiesterase, PDE5, with a Ki value of 1.3 µM. It inhibits calcium- and cAMP-selective PDEs with Ki values of >1,000 and 915 µM, respectively. MY-5445 has been shown to relax intact strips of rat aorta with an EC50 value of 4 µM.Formal Name:...

Keywords:	N-(3-chlorophenyl)-4-phenyl-1-phthalazinamine
Application:	PDE5 inhibitor
CAS	78351-75-4
MW:	331.8 D

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