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CDPPB
Item number: Cay34132-5
CDPPB is a positive allosteric modulator (PAM) of metabotropic glutamate receptor 5 (mGluR5). It potentiates glutamate-induced increases in intracellular calcium in CHO cells expressing mGluR5 (EC50s = 10 and 20 nM for the human and rat receptor, respectively). CDPPB (30 mg/kg, s.c.) inhibits amphetamine-induced...
| Keywords: | 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)-benzamide |
| Application: | MGluR5 positive allosteric modulator |
| CAS | 781652-57-1 |
| MW: | 364.4 D |
From 45.00€
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CDPPB
Item number: TGM-T22641-100mg
Description: CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5). Target: GluR. Smiles: O=C(Nc1cc(nn1-c1ccccc1)-c1ccccc1)c1cccc(c1)C#N. References: Kinney GG, et, al. A novel selective positive allosteric modulator of metabotropic glutamate...
| Application: | MGluR5 positive allosteric modulator |
| CAS | 781652-57-1 |
| MW: | 364.4 D |
From 40.00€
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