2 products were found matching "781613-23-8"!
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Tesevatinib
Item number: TGM-TQ0166-10mg
Description: Tesevatinib (XL-647) is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4). Target: VEGFR, Ephrin Receptor, EGFR, FLT. Smiles: COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C)C[C@H]2C1. References: Gendreau...
| Keywords: | EXEL-7647, XL-647, KD-019 |
| Application: | Targets epidermal growth factor receptor [EC:2.7.10.1] (EGFR, ERBB1) |
| CAS | 781613-23-8 |
| MW: | 491.39 D |
From 108.00€
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XL647
Item number: Cay27049-1
XL647 is a multi-kinase inhibitor (IC50s = 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, FLT4, and EphB4, respectively). It is selective for these kinases over a panel of 10 tyrosine kinases and 55 serine/threonine kinases at 10 µM. XL647 inhibits growth of A431 cells expressing wild-type EGFR and H1975...
| Keywords: | EXEL-7647, Tesevatinib,... |
| Application: | Multi-kinase (EGFR, ErbB2, KDR, FLT4, EphB4) inhibitor |
| CAS | 781613-23-8 |
| MW: | 491.4 D |
From 133.00€
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