Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 = 10-50 nM), both isoforms of PP2A (IC50 = 0.5 nM) and PP3 (IC50 = 4 nM). It is a very weak inhibitor of PP2B (IC50 > 2 µM) and does...

Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by...

Potent inhibitor of protein phosphatases, especially the PP-1 and PP-2 classes, in numerous cell types. Non-phorbol type tumor promoter.

Okadaic acid is a non-phorbol type tumor promoter. Potent inhibitor of protein phosphatases in numerous cell types.

Potent inhibitor of protein phosphatases, especially the PP-1 and PP-2A classes, in numerous cell types. Solubility: Soluble in DMSO, methanol and ethanol. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the...