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ICG-001
ICG-001

Item number: TGM-T6113-100mg

Description: ICG-001 antagonizes Wnt/beta-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 µM, but is not the related transcriptional coactivator p300. Target: Epigenetic Reader Domain, Apoptosis, Wnt/beta-catenin. Smiles:...
Application: beta-catenin / CBP inhibitor
CAS 780757-88-2
MW: 548.63 D
From 31.00€ *
Review
ICG-001
ICG-001

Item number: Cay16257-1

ICG-001 is a small molecule inhibitor of beta-catenin/cyclic AMP responsive element binding protein (CREB) binding protein (CBP)-mediated transcription (IC50 = 3 µM). By binding CBP, thus blocking interaction with beta-catenin, it selectively induces apoptosis in transformed colon cells but not in normal cells and...
Keywords: (6S,9aS)-hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrim...
Application: beta-catenin / CBP inhibitor
CAS 780757-88-2
MW: 548.6 D
From 49.00€ *
Review