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GNF-5
GNF-5

Item number: LKT-G5322.100

Abl inhibitor.
Application: Abl inhibitor
CAS 778277-15-9
MW: 418.38 D
From 73.00€ *
Review
GNF-5
GNF-5

Item number: Cay16254-10

GNF-5 is an allosteric inhibitor of Bcr-Abl (IC50 = 0.121 µM) and a derivative of GNF-2 (Cay-16253). It also inhibits the Bcr-Abl mutants Bcr-AblG250E, Bcr-AblE255V, and Bcr-AblM351T (IC50s = 4.52, 0.38, and 0.93 µM, respectively). GNF-5 inhibits the growth of Ba/F3 cells (IC50 = 0.145 µM). It reduces viral titers...
Keywords: N-(2-hydroxyethyl)-3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-benzamide
Application: BCR-Abl inhibitor
CAS 778277-15-9
MW: 418.4 D
From 52.00€ *
Review