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Item number: TGM-T3135-100mg

Description: KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane. Target: CFTR, Autophagy. Smiles: Clc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12. References: Robert R, et al. Mol Pharmacol. 2008...

Application:	CFTR F508del processing correction
CAS	774549-97-2
MW:	422.33 D

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KM 11060

Item number: Cay23481-10

KM 11060 is a small molecule that corrects the processing of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing the F508 deletion (F508del) mutation carried by 90% of cystic fibrosis patients. It increases cell surface expression and restores chloride transport function of F508del-CFTRs in...

Keywords:	7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-quinoline
Application:	CFTR F508del processing correction
CAS	774549-97-2
MW:	422.3 D

From 124.00€ *

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