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Item number: TGM-T7693-100mg

Description: Thiorphan is an neprilysin inhibitor (NEP, IC50 : 0.007 µM). Target: Neprilysin. Smiles: OC(=O)CNC(=O)C(CS)Cc1ccccc1. References: Chicau-Chovet M , Dubrasquet M , Chariot J , et al. Thiorphan and acetorphan inhibit gastric secretion by a central, non-opioid mechanism in the rat[J]. European Journal of...

Application:	Potent neprilysin inhibitor
CAS	76721-89-6
MW:	253.32 D

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Thiorphan

Item number: Cay15600-5

Thiorphan is an inhibitor of neprilysin (NEP, IC50 = 0.007 µM). It selectivity inhibits NEP over NEP2 (IC50 = 22 µM), as well as angiotensin-converting enzyme (ACE) and endothelin-converting enzyme 1 (ECE1, Kis = >0.1 and >10 µM, respectively, in cell-free assays). Thiorphan (10 µM) increases bradykinin-induced...

Keywords:	DL-Thiorphan, N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]-glycine
Application:	Potent neprilysin inhibitor
CAS	76721-89-6
MW:	253.3 D

From 85.00€ *

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