- Search results for 761439-42-3
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4 products were found matching "761439-42-3"!
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Item number: Cay17670-5
Human anaplastic lymphoma kinase (ALK) is an oncogene that is amplified in neuroblastomas and when juxtaposed with various fusion partners, its constitutive kinase activity is associated with the development of a type of anaplastic large cell lymphoma (ALCL). TAE684 is an ALK inhibitor that blocks the proliferation...
Keywords: | NVP-TAE684,... |
Application: | ALK inhibitor |
CAS | 761439-42-3 |
MW: | 614.2 D |
From 52.00€
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Item number: SYN-1159-M001
Soluble in DMSO or ethanol. TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR. Target: ALK , Kinase Group: RTK , Substrate: Tyrosine
Keywords: | NVP-TAE684 |
Application: | ALK inhibitor |
CAS | 761439-42-3 |
MW: | 614,2 D |
From 139.00€
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Item number: LKT-N8760.1
ALK, c-Fes, LRRK2 inhibitor.
Keywords: | TAE684 |
Application: | ALK, c-Fes, LRRK2 inhibitor |
CAS | 761439-42-3 |
MW: | 614.21 D |
From 142.00€
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Item number: TGM-T2251-5mg
Description: NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM). Target: Apoptosis, ALK. Smiles: N(C1=C(S(C(C)C)(=O)=O)C=CC=C1)C2=NC(NC3=C(OC)C=C(C=C3)N4CCC(CC4)N5CCN(C)CC5)=NC=C2Cl. References: Galkin AV, et al. Proc Natl Acad Sci U S A, 2007, 104(1), 270-275.
Keywords: | TAE684 |
Application: | ALK inhibitor |
CAS | 761439-42-3 |
MW: | 614.2 D |
From 52.00€
*