- Search results for 761437-28-9
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3 products were found matching "761437-28-9"!
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Item number: TGM-T1918-100mg
Description: NVP-TAE 226 (TAE226) is a potent FAK inhibitor (IC50: 5.5 nM), exhibiting even greater efficacy against Pyk2 (IC50: 3.5 nM), and is 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK. Target: IGF-1R, FAK, Apoptosis, c-Met/HGFR, PYK2. Smiles:...
Keywords: | TAE226 |
Application: | FAK inhibitor |
CAS | 761437-28-9 |
MW: | 468.94 D |
From 41.00€
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Item number: Cay17685-1
NVP-TAE226 is an inhibitor of focal adhesion kinase (FAK, IC50 = 5.5 nM) and the related proline-rich tyrosine kinase 2-beta (PYK2beta, IC50 = 5 nM). It can also inhibit the insulin-like growth factor 1 receptor (IC50 = 0.16 µM) as well as the activity of its downstream target genes such as MAPK and Akt. NVP-TAE226...
Keywords: | TAE226, 2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-benzamide |
Application: | FAK inhibitor |
CAS | 761437-28-9 |
MW: | 468.9 D |
From 60.00€
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Item number: LKT-T0216.1
FAK inhibitor.
Keywords: | NVP-TAE226 |
Application: | FAK inhibitor |
CAS | 761437-28-9 |
MW: | 468.94 D |
From 129.00€
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