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Fludarabine Phosphate
Item number: TGM-T6501-100mg
Description: Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by...
| Keywords: | F-ara-A (NSC 312887) Phosphate, F-ara-AMP, NSC 312887 Phosphate, fludara Phosphate |
| Application: | Targets ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] (RRM1) |
| CAS | 75607-67-9 |
| MW: | 365.21 D |
From 33.00€
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Fludarabine Phosphate
Item number: LKT-F4782.10
Highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates than alkylating agents. It is a purine analog which inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase.
| CAS | 75607-67-9 |
| MW: | 365,21 D |
From 99.00€
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Fludarabine Phosphate
Item number: Cay14251-10
Fludarabine phosphate is a prodrug form of fludarabine (Cay-14128) and 2-fluoro-ara-ATP. It is dephosphorylated in vivo to fludarabine and re-phosphorylated intracellularly to the active form, 2-fluoro-ara-ATP, which inhibits DNA synthesis. Fludarabine phosphate reduces viability of, and induces apoptosis in,...
| Keywords: | F-ara-AMP, NSC 312887, NSC 328002, 2-fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine |
| Application: | Antineoplastic |
| CAS | 75607-67-9 |
| MW: | 365.2 D |
From 92.00€
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