- Search results for 755038-02-9
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4 products were found matching "755038-02-9"!
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Item number: Cay17385-1
Polo-like kinases (Plks) are serine/threonine kinases with key roles in cell cycling. BI-2536 is a 2-aminopyrimidine-containing inhibitor of Plk1 (IC50 = 0.83 nM). It displays 4- and 11-fold selectivity for Plk1 over Plk2 and Plk3, respectively. BI-2536 induces mitotic arrest and apoptosis in diverse human cancer...
Keywords: | 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-... |
Application: | Plk1 inhibitor |
CAS | 755038-02-9 |
MW: | 521.7 D |
From 50.00€
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Item number: SYN-1019-M001
Soluble in DMSO, Ethanol. Polo-like kinase 1 (Plk1) is a regulator of the cell cycle that has been implicated in the pathology of many cancers. BI-2536 is a potent and selective small-molecule inhibitor of mammalian Plk1. It has inhibitory activity at subnanomolar concentrations and inhibits tumor growth in...
Keywords: | (R)-BI2536 |
Application: | PLK1 inhibitor |
CAS | 755038-02-9 |
MW: | 521,7 D |
From 106.00€
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Item number: LKT-B3200.1
PLK1 inhibitor.
Keywords: | BI2536 |
Application: | PLK1 inhibitor |
CAS | 755038-02-9 |
MW: | 521.65 D |
From 104.00€
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![BI-2536 BI-2536](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number: BPS-82062-1
BI-2536 is a potent, ATP-competitive, well tolerated and effects Polo-like kinases (Plks) as well as a pan-BET (bromodomain and extra-terminal motif) family inhibitor. BI-2536 has an IC50 of 0.83 and 25 nM with PLK1 and BRD4 inhibitor, respectively. BI-2536 also blocks the activities of Plk2 and Plk3 to a slightly...
Keywords: | BI2536, BI 2536, |
Application: | pan-BET (bromodomain and extra-terminal motif) family inhibitor, Plk1 inhibitor |
CAS | 755038-02-9 |
MW: | 521,7 D |
From 1,204.00€
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