4 products were found matching "755038-02-9"!
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BI-2536
Item number: Cay17385-1
Polo-like kinases (Plks) are serine/threonine kinases with key roles in cell cycling. BI-2536 is a 2-aminopyrimidine-containing inhibitor of Plk1 (IC50 = 0.83 nM). It displays 4- and 11-fold selectivity for Plk1 over Plk2 and Plk3, respectively. BI-2536 induces mitotic arrest and apoptosis in diverse human cancer...
| Keywords: | 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-... |
| Application: | Plk1 inhibitor |
| CAS | 755038-02-9 |
| MW: | 521.7 D |
From 50.00€
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(R)-BI-2536
Item number: SYN-1019-M001
Soluble in DMSO, Ethanol. Polo-like kinase 1 (Plk1) is a regulator of the cell cycle that has been implicated in the pathology of many cancers. BI-2536 is a potent and selective small-molecule inhibitor of mammalian Plk1. It has inhibitory activity at subnanomolar concentrations and inhibits tumor growth in...
| Keywords: | (R)-BI2536 |
| Application: | PLK1 inhibitor |
| CAS | 755038-02-9 |
| MW: | 521,7 D |
From 106.00€
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BI-2536
Item number: LKT-B3200.1
PLK1 inhibitor.
| Keywords: | BI2536 |
| Application: | PLK1 inhibitor |
| CAS | 755038-02-9 |
| MW: | 521.65 D |
From 104.00€
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BI-2536
Item number: BPS-82062-1
BI-2536 is a potent, ATP-competitive, well tolerated and effects Polo-like kinases (Plks) as well as a pan-BET (bromodomain and extra-terminal motif) family inhibitor. BI-2536 has an IC50 of 0.83 and 25 nM with PLK1 and BRD4 inhibitor, respectively. BI-2536 also blocks the activities of Plk2 and Plk3 to a slightly...
| Keywords: | BI2536, BI 2536, |
| Application: | pan-BET (bromodomain and extra-terminal motif) family inhibitor, Plk1 inhibitor |
| CAS | 755038-02-9 |
| MW: | 521,7 D |
From 1,204.00€
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