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Item number: TGM-T14941-100mg

Description: CGP37157 (7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one) is a Na+/Ca2+ exchanger inhibitor, inhibits Na+-induced Ca2+ release from mitochondria in guinea pig heart with IC50 of 0.8 µM. Target: Na+/Ca2+ Exchanger. Smiles: Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1. References: Chiesi M, et...

Keywords:	7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one
CAS	75450-34-9
MW:	324.22 D

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CGP 37157

Item number: Cay15611-10

CGP 37157 is a benzothiazepine that acts as a selective inhibitor of the mitochondrial sodium-calcium exchanger (IC50 = 0.36 µM in isolated mitochondria). It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 is commonly used to study the role...

Keywords:	7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one
CAS	75450-34-9
MW:	324.2 D

From 197.00€ *

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