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DMAT
Item number: TGM-T7390-100mg
Description: DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM). Target: Casein Kinase. Smiles: CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1. References: Lawnicka H , Kowalewicz-Kulbat M , Sicinska P , et al. Anti-neoplastic effect of protein kinase CK2 inhibitor,...
| Keywords: | CK2 Inhibitor, Casein kinase II Inhibitor |
| Application: | Potent high affinity ATP-competitive casein kinase II (CK2) inhibitor |
| CAS | 749234-11-5 |
| MW: | 476.79 D |
From 57.00€
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DMAT
Item number: Cay21182-1
DMAT is a cell-permeable inhibitor of casein kinase 2 (CK2, IC50 = 0.13 µM). It also inhibits Pim-1, Pim-3, HIPK2, and HIPK3 (IC50s = 0.15, 0.097, 0.37, and 0.59 µM, respectively). DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts.Formal Name:...
| Keywords: | 2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole, Casein Kinase II Inhibitor II,... |
| Application: | CK2 inhibitor |
| CAS | 749234-11-5 |
| MW: | 476.8 D |
From 52.00€
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DMAT
Item number: AG-CR1-3654-M001
Solid. Soluble in DMSO (10mg/ml). Potent high affinity ATP-competitive inhibitor of casein kinase II (CK2) (IC50=0.13µM). Inhibits CK2 in rat liver with >1000-fold greater selectivity for CK2 than for CK1 (IC50=140nM and >200 &mu,M, respectively), DYRK1A and DYRK2 inhibitor (IC50= ~0.4µM for both), Shown to inhibit...
| Keywords: | 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole, 4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine |
| Application: | Potent high affinity ATP-competitive casein kinase II (CK2) inhibitor |
| CAS | 749234-11-5 |
| MW: | 476,8 D |
From 33.00€
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