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Luminespib
Luminespib

Item number: TGM-T1989-100mg

Description: Luminespib (VER-52296) is a novel HSP90 inhibitor with IC50 values of 7.8 nM for HSP90alpha and 21 nM for HSP90beta in a cell-free assay. Target: HSP, Apoptosis, Autophagy. Smiles: CCNC(=O)c1noc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(C(C)C)c(O)cc1O. References: Eccles, Suzanne A., et al. NVP-AUY922: A Novel...
Keywords: NVP-AUY922, VER-52296, AUY922
Application: Antineoplastic, Hsp 90 inhibitor
CAS 747412-49-3
MW: 465.54 D
From 52.00€ *
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NVP-AUY922
NVP-AUY922

Item number: Cay10012698-5

Hsp90 is a molecular chaperone of many different kinases, transcription factors, and hormone receptors involved in signal transduction, cell cycle regulation, and apoptosis. In addition to its important function in normal cell homeostasis, a high affinity form of Hsp90 is prevalent in tumor cells. Hsp90 inhibition...
Keywords: VER 52296, 5-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]-3-isoxazolecarboxamide
Application: Hsp90 Inhibitor
CAS 747412-49-3
MW: 465.5 D
From 209.00€ *
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NVP-AUY922
NVP-AUY922

Item number: LKT-N8660.1

Isoxazole derivative, HSP90 inhibitor.
Keywords: VER-52296
Application: Isoxazole derivative, HSP90 inhibitor
CAS 747412-49-3
MW: 465.54 D
From 109.00€ *
Review