Description: Cefotetan Sodium, a second-generation cephalosporin, cephamycin antibiotic, is active against a wide range of both aerobic and anaerobic gram-negative and gram-positive bacteria. Cefotetan disrupts the cell wall synthesis by binding to penicillin-binding proteins. Target: Others. Smiles:...

Cefotetan is a cephamycin antibiotic that is active against both Gram-positive and Gram-negative bacteria including isolates of E. coli, S. aureus, K. pneumoniae, and P. maltophilia (MICs = 0.03-32 mg/ml). It reduces mortality by 50% in a rabbit model of fecal peritonitis when administered at a dose of 25 mg/kg...