Description: 3-Chloro-L-Tyrosine (Chlorotyrosine), a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular, myeloperoxidase halogenates tyrosine residues in plasma proteins and generates 3-chlorotyrosine (CY)....

3-chloro-L-Tyrosine is a derivative of L-tyrosine. It is formed from a reaction between the myeloperoxidase (MPO) product hypochlorous acid and L-tyrosine and has been used as a biomarker of oxidative damage induced by MPO. Plasma and atherosclerotic plaque levels of 3-chloro-L-tyrosine are increased in patients...