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Anagliptin
Item number: TGM-T7133-100mg
Description: Anagliptin (SK-0403) is a potent inhibitor of DPP-4 (IC50 of 3.8 nM) used in the treatment of type 2 diabetes mellitus. Target: DPP-4, Proteasome. Smiles: Cc1cc2ncc(cn2n1)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N. References: Ervinna N, et al. Anagliptin, a DPP-4 inhibitor, suppresses proliferation of...
| Keywords: | SK-0403 |
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 739366-20-2 |
| MW: | 383.45 D |
From 39.00€
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Anagliptin
Item number: Cay36188-1
Anagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 3.8 nM). It is selective for DPP-4 over DPP-8 and DPP-9 (IC50s = 68 and 60 nM, respectively). Dietary administration of anagliptin (0.05 and 0.3% w/w) decreases plasma DPP-4 activity, increases plasma GLP-1 levels, suppresses food intake and body...
| Keywords: | N-[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]-2-methylpropyl]-2-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxamide |
| Application: | DPP-4 inhibitor |
| CAS | 739366-20-2 |
| MW: | 383.5 D |
From 60.00€
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