Description: Prednicarbate (Hoe 777) is a Corticosteroid Hormone Receptor Agonist. Prednicarbate has antipruritic, anti-inflammatory, and vasoconstrictive properties. It also decreases the number of circulating lymphocytes by inhibiting the production of vasodilators such as nitric oxide and prostacyclin. Target:...

Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone (Cay-20866). It has anti-inflammatory activity comparable to that of desoximetasone in various murine models when administered topically but lacks activity when administered subcutaneously. Topical administration of prednicarbate (2 drops...