Description: BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2. Target: HIV Protease. Smiles: Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)N1CCCCS1(=O)=O. References: Dicker IB, et al. J Biol Chem, 2007, 282(43), 31186-31196.

HIV-1 integrase inhibitor 1 is an inhibitor of HIV-1 integrase DNA strand transfer (IC50 = 14 nM). It is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), when used at a concentration of 10 µM in a fluorescence-based...