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Syk Inhibitor II
Syk Inhibitor II

Item number: TGM-T4348-1mL

Description: Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM). Target: 5-HT Receptor, Syk. Smiles: NCCNc1ncc(C(N)=O)c(Nc2cccc(c2)C(F)(F)F)n1. References: Hisamichi H,etal.Synthetic studies on novel Syk inhibitors. Part 1:...
Application: Syk inhibitor
CAS 726695-51-8
MW: 340.3 D
From 42.00€ *
Review
Syk Inhibitor II
Syk Inhibitor II

Item number: Cay18202-1

Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs and mediates downstream signaling. Syk inhibitor II is a cell-permeable, pyrimidine-carboxamide compound that selectively and reversibly blocks Syk (IC50 = 41 nM) in an...
Keywords: Spleen Tyrosine Kinase Inhibitor II, 2-[(2-aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide
Application: Syk inhibitor
CAS 726695-51-8
MW: 340.3 D
From 164.00€ *
Review