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Item number: TGM-T13411-100mg

Description: ZLN024 is an activator of AMPK allosteric. ZLN024 allosterically stimulates active AMPK heterotrimers and the inactive alpha1 subunit truncations alpha1 (1-394) and alpha1 (1-335) but not alpha1 (1-312). Target: AMPK. Smiles: Cc1ccc(OCCSc2ncccn2)c(Br)c1. References: Zhang LN, et al. Novel small-molecule...

Application:	AMPK activator
CAS	723249-01-2
MW:	325.22 D

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ZLN024

Item number: Cay21644-10

ZLN024 is an allosteric activator of AMP-activated protein kinase (AMPK) heterotrimers (EC50s = 0.42 and 0.95 µM for alpha1beta1gamma1 and alpha2beta1gamma1, respectively). Activation of AMPK by ZLN024 requires phosphorylation of AMPK on Thr172, and ZLN024 protects Thr172 from dephosphorylation by protein...

Keywords:	2-[[2-(2-bromo-4-methylphenoxy)ethyl]thio]-pyrimidine
Application:	AMPK activator
CAS	723249-01-2
MW:	325.2 D

From 132.00€ *

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