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4-Oxoisotretinoin
4-Oxoisotretinoin

Item number: TGM-T3559-100mg

Description: 4-Oxoisotretinoin (Ro 22-6595) is the major blood metabolite. Target: Others. Smiles: C(=C/C(=C/C=C/C(=C\C(O)=O)/C)/C)\C=1C(C)(C)CCC(=O)C1C. References: Lucio Vilar,et al. The Role of Isotretinoin Therapy for Cushing's Disease: Results of a Prospective Study. International Journal of Endocrinology...
Keywords: Oxoretinoic acid, 4-Oxoisotretinoin, Ro 22-6595
Application: Active isotretinoin metabolite
CAS 71748-58-8
MW: 314.42 D
From 57.00€ *
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4-oxo Isotretinoin
4-oxo Isotretinoin

Item number: Cay34388-10

4-oxo Isotretinoin is an active metabolite of the retinoid isotretinoin (Cay-21648). It is formed from isotretinoin by several cytochrome P450 (CYP450) isoforms, including CYP3A, CYP2B6, and CYP2C19. 4-oxo Isotretinoin (10 µM) increases protein expression of cytokeratin 7 (CK7) and CK19 in normal human epidermal...
Keywords: Ro 22-6595, 13-cis-4-oxo-retinoic acid
Application: Active isotretinoin metabolite
CAS 71748-58-8
MW: 314.4 D
From 52.00€ *
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13-cis-4-Oxoretinoic acid
13-cis-4-Oxoretinoic acid

Item number: CDX-O0048-M001

Dark yellow powder. Soluble in acetone, chloroform, ethanol (slightly) or ether. Major active metabolites of 13-cis-retinoic acid (important drug in dermatology and treatment of neuroblastoma) with effects on gene transcription that regulate growth, differentiation and inflammation in normal and neoplastic skin...
Keywords: 4-Oxoisotretinoin, Ro 22-6595
Application: Active 13-cis-retinoic acid metabolite, Reference compound
CAS 71748-58-8
MW: 314,42 D
From 168.00€ *
Review