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Item number: TGM-T60437-100mg

Description: PNU-282987 (free base) is a potent agonist of alpha7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM and a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. It can be used for central and peripheral nervous system studies[1]. Target: 5-HT Receptor, AChR. Smiles:...

Application:	nAChR (CHRNA7) agonist
CAS	711085-63-1
MW:	264.75 D

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PNU 282987

Item number: Cay17424-10

PNU 282987 is a potent agonist of alpha7-containing neuronal nicotinic acetylcholine receptors (nAChRs, Ki = 26 nM for the rat receptor). It has negligible activity against alpha1beta1gammadelta and alpha3beta4 nAChRs as well as a panel of monoamine, muscarinic, glutamate, and GABA receptors, except 5-HT3 (Ki = 930...

Keywords:	N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-benzamide
Application:	nAChR (CHRNA7) agonist
CAS	711085-63-1
MW:	264.8 D

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