1 products were found matching "709026-60-8"!

Lipid-based Drug Delivery Tools from Cayman Chemical

Lipid-based drug delivery (LBDD) systems, such as LNPs, liposomes, and solid lipid nanoparticles (SLNs), are customizable platforms for the targeted delivery of pharmaceuticals and other therapeutic agents to cells and tissues. LBDD overcomes obstacles associated with conventional therapeutic formulations by encapsulating bioactive molecules in a lipid vesicle, which increases their bioavailability, distribution, and plasma half-life, and decreases systemic toxicity induced by off-target activity. The versatility of LBDD formulations is achievable in part through the diversity of lipids available for these applications. Our partner Cayman Chemical offers high-quality lipid components that can be used to build lipid particles as research tools, as well LNP Exploration Kits and Custom Lipid Synthesis to support preclinical research programs.

Learn more here:

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Blog Article: Lipid-based Drug Delivery Development - Part 1
Blog Article: Lipid-based Drug Delivery Development - Part 2
Caymans Guide to Lipid Nanoparticle Formulation

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Lipid-based Drug Delivery Tools

Sphingosine-1-phosphate (d16:1)

Item number: Cay9002921-1

C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P, Cay-62570) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma...

Keywords:	C16 S1P, C16 Sphingosine-1-phosphate, S1P (d16:1), 2S-amino-1-(dihydrogen phosphate), 4E-hexadecene-1,3R-diol
Application:	S1PR1/S1PR2/S1PR3 ligand
CAS	709026-60-8
MW:	351.4 D

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