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Item number: TGM-TQ0304-100mg

Description: Metixene hydrochloride hydrate has potential anticholinergic activity and inhibits the binding of quinine ring benzoate (QNB) to muscarine receptors, with IC50 and Ki values of 55 nM and 15 nM, respectively. Metixene hydrochloride hydrate can be used to prevent and treat Parkinson's disease. Target:...

Application:	Antiparkinsonian, Smooth muscle relaxant, Muscarinic acetylcholine receptor antagonist
CAS	7081-40-5
MW:	363.95 D

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Metixene (hydrochloride hydrate)

Item number: Cay39825-1

Metixene is an antagonist of muscarinic acetylcholine receptors (mAChRs, Ki = 15 nM for the rat receptor). It also inhibits bovine acetylcholinesterase (AChE) by 43% when used at the concentration 10 µM and butyrylcholinesterase (BChE, IC50 = 1.6 µM for the horse enzyme) in cell-free assays. Metixene reduces the...

Keywords:	Methixine, 1-methyl-3-(9H-thioxanthen-9-ylmethyl)-piperidine, monohydrochloride, monohydrate
Application:	Muscarinic acetylcholine receptor antagonist
CAS	7081-40-5
MW:	363.9 D

From 34.00€ *

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