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Mitoxantrone dihydrochloride
Item number: TGM-T0158-100mg
Description: Mitoxantrone dihydrochloride (NSC-301739) is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. It is a type II topoisomerase inhibitor. Target: PKC, Topoisomerase. Smiles: Cl.OCCNCCNc1c2C(=O)c3c(O)ccc(O)c3C(=O)c2c(NCCNCCO)cc1.Cl. References: Seitz M. Curr Opin...
| Keywords: | mitozantrone dihydrochloride, NSC-301739, Mitoxantrone hydrochloride, Mitoxantrone 2HCl |
| CAS | 70476-82-3 |
| MW: | 517.4 D |
From 49.00€
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Mitoxantrone (hydrochloride)
Item number: Cay14842-10
Mitoxantrone is an inhibitor of DNA topoisomerase IIalpha and HIV-1 integrase (IC50s = 5.3 and 3.8 µM, respectively). It intercalates into DNA in a cell-free assay when used at a concentration of 2 µM, as well as inhibits DNA synthesis and induces DNA-protein crosslinks in vitro in a concentration-dependent manner....
| Keywords: | NCI 301739, NSC 301739, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione, dihydrochloride |
| Application: | Topoisomerase II inhibitor, HIV-1 integrase inhibitor |
| CAS | 70476-82-3 |
| MW: | 517.4 D |
From 44.00€
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Mitoxantrone Dihydrochloride
Item number: LKT-M3379.50
A cytostatic anthraquinone derivative. An antitumor agent that interacts with DNA by intercallation.
| Application: | Anticancer agent |
| CAS | 70476-82-3 |
| MW: | 517,41 D |
From 184.00€
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