- Search results for 702675-74-9
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3 products were found matching "702675-74-9"!
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Item number: Cay14932-5
BX-795 is a multi-kinase inhibitor that is an ATP-competitive inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1) and TANK-binding kinase 1 (TBK1, IC50s = 6 and 11 nM, respectively). It also inhibits the CAMK family kinases AMPK-related kinase 5 (NUAK1, IC50 = 5 nM) and microtubule affinity-regulating...
Keywords: | N-[3-[[5-iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide |
Application: | PDPK1 inhibitor |
CAS | 702675-74-9 |
MW: | 591.5 D |
From 109.00€
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Item number: SYN-1026-M001
Soluble in DMSO or ethanol. BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of...
Keywords: | BX795 |
Application: | PDPK1 inhibitor |
CAS | 702675-74-9 |
MW: | 591,5 D |
From 100.00€
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![BX-795 BX-795](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number: LKT-B9200.5
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
Keywords: | BX795 |
Application: | PDPK1 inhibitor |
CAS | 702675-74-9 |
MW: | 591.47 D |
From 139.00€
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