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Vercirnon
Item number: TGM-T17225-100mg
Description: Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases. Target: CCR. Smiles: CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(Cl)cc1C(=O)c1cc[n+]([O-])cc1
| Keywords: | CCX282-B, GSK-1605786, Traficet-EN |
| Application: | Targets C-C chemokine receptor type 9 (CCR9, CDw199) |
| CAS | 698394-73-9 |
| MW: | 444.93 D |
From 106.00€
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Vercirnon
Item number: Cay23131-1
Vercirnon is an orally bioavailable antagonist of chemokine receptor 9 (CCR9) with an IC50 value of 5.4 nM for inhibition of CCL25-induced calcium mobilization in Molt-4 cells. It is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s = >10 µM for all). It also inhibits CCL25-induced Molt-4 chemotaxis in 0.1%...
| Keywords: | CCX282-B, GSK1605786, N-[4-chloro-2-[(1-oxido-4-pyridinyl)carbonyl]phenyl]-4-(1,1-dimethylethyl)-benzenesulfonamide |
| Application: | Chemokine receptor 9 antagonist, antiinflammatory |
| CAS | 698394-73-9 |
| MW: | 444.9 D |
From 111.00€
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