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CRT0044876
Item number: TGM-T6456-100mg
Description: CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 µM. Target: DNA/RNA Synthesis. Smiles: OC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1. References: Madhusudan S, et al. Nucleic Acids Res. 2005, 33(15), 4711-4724.
| Keywords: | 7-Nitroindole-2-Carboxylic Acid, NSC 69877, NSC 69877,7-NO2-ICA |
| Application: | Cell-permeable Ape-1 inhibitor |
| CAS | 6960-45-8 |
| MW: | 206.15 D |
From 31.00€
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DNA Base Excision Repair Pathway Inhibitor
Item number: Cay16348-10
Apurinic/apyrimidinic endonuclease-1 (Ape-1) is involved in base excision repair, cleaving the phosphodiester linkage that is 5' to the abasic site to produce a single strand break. DNA base excision repair pathway inhibitor is a cell-permeable inhibitor of Ape-1 (IC50 = 3-11 µM). Although not toxic to cells by...
| Keywords: | 7-Nitroindole-2-Carboxylic Acid, CRT0044876, NSC 69877, 7-nitro-1H-indole-2-carboxylic acid |
| Application: | Cell-permeable Ape-1 inhibitor |
| CAS | 6960-45-8 |
| MW: | 206.2 D |
From 61.00€
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