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Item number: Cay21030-50

(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the...

Keywords:	BVU, 5-[(1E)-2-bromoethenyl]-2,4(1H,3H)-pyrimidinedione
CAS	69304-49-0
MW:	217 D

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